Surfactin C1
(Synonyms: 表面活性素) 目录号 : GC39448
A lipopeptide biosurfactant
Cas No.:24730-31-2
Sample solution is provided at 25 µL, 10mM.
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Quality Control & SDS
- View current batch:
- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Surfactin is a cyclic lipopeptide biosurfactant produced by various strains of Bacillus.1 It is composed of a variable heptapeptide and a β-hydroxy fatty acid that ranges in length from 12- to 15 carbons, which generates several isoforms.2 Surfactins interact with and destabilize biological membranes, resulting in a variety of diverse biological activities, including antibacterial, anti-inflammatory, and anticancer activities.1 This surfactin isoform contains the heptapeptide L-Glu-L-Leu-D-Leu-L-Val-L-Asp-D-Leu-L-Leu and is linked to a 15-carbon β-hydroxy fatty acid with the iso branching configuration.
1.Wu, Y.-S., Ngai, S.-C., Goh, B.-H., et al.Anticancer activities of surfactin and potential application of nanotechnology assisted surfactin deliveryFront. Pharmacol.8761(2017) 2.Kowall, M., Kluge, J.V., Stein, T., et al.Separation and characterization of surfactin isoforms produced by Bacillus subtilis OKB 105J. Colloid Interface Sci.204(1)1-8(1998)
| 制备储备液 | |||
 |
1 mg | 5 mg | 10 mg |
| 1 mM | 0.9649 mL | 4.8247 mL | 9.6493 mL |
| 5 mM | 0.193 mL | 0.9649 mL | 1.9299 mL |
| 10 mM | 0.0965 mL | 0.4825 mL | 0.9649 mL |
| 第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量） | ||||||||||
| 给药剂量 | mg/kg |  |
动物平均体重 | g | |
每只动物给药体积 | ul | |
动物数量 | 只 |
| 第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系GLPBIO为您提供正确的澄清溶液配方） | ||||||||||
| % DMSO % % Tween 80 % saline | ||||||||||
| 计算重置 | ||||||||||
计算结果:
工作液浓度： mg/ml；
DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，
体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL saline，混匀澄清。
1. 首先保证母液是澄清的；
2.
一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。