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Tauroursodeoxycholic Acid-d4 MaxSpec® Standard Sale

(Synonyms: Tauroursodeoxycholic acid-d4; TUDCA-d4; UR 906-d4) 目录号 : GC48468

A quantitative analytical standard guaranteed to meet MaxSpec identity, purity, stability, and concentration specifications

Tauroursodeoxycholic Acid-d4 MaxSpec® Standard Chemical Structure

Cas No.:2410279-94-4

规格 价格 库存 购买数量
100µg
¥3,512.00
现货

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Sample solution is provided at 25 µL, 10mM.

产品文档

Quality Control & SDS

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产品描述

Tauroursodeoxycholic acid-d4 (TUDCA-d4) is intended for use as an internal standard for the quantification of tauroursodeoxycholic acid by GC- or LC-MS. TUDCA is a taurine-conjugated form of the secondary bile acid ursodeoxycholic acid .1,2 TUDCA is found in small quantities in human bile but at a higher concentration in the bile of black bears.2 It demonstrates anti-apoptotic activity in rodent models of tauopathy, Huntington's disease, ischemic brain injury, and retinal disorders.3,2

TUDCA-d4 MaxSpec® Standard is a quantitative grade standard of TUDCA-d4 that has been prepared specifically for mass spectrometry or any application where quantitative reproducibility is required. The solution has been prepared gravimetrically and is supplied in a deactivated glass ampule sealed under argon. The concentration was verified by comparison to an independently prepared calibration standard. The verified concentration is provided on the certificate of analysis. This TUDCA-d4 MaxSpec® standard is guaranteed to meet identity, purity, and stability specifications and is provided with a batch-specific Certificate of Analysis. Ongoing stability testing is performed to ensure the concentration remains accurate throughout the shelf life of the product. Note: The amount of solution added to the vial is in excess of the listed amount. Therefore, it is necessary to accurately measure volumes for preparation of calibration standards. Follow recommended storage and handling conditions to maintain product quality.

1.Beuers, U.Effects of bile acids on hepatocellular signaling and secretionYale J. Biol. Med.70(4)341-346(1997) 2.Boatright, J.H., Nickerson, J.M., Moring, A.G., et al.Bile acids in treatment of ocular diseaseJ. Ocul. Biol. Dis. Infor.2(3)149-159(2009) 3.Vang, S., Longley, K., Steer, C.J., et al.The unexpected uses of urso- and tauroursodeoxycholic acid in the treatment of non-liver diseasesGlob. Adv. Health Med.3(3)58-69(2014)

Chemical Properties

Cas No. 2410279-94-4 SDF
别名 Tauroursodeoxycholic acid-d4; TUDCA-d4; UR 906-d4
Canonical SMILES C[C@H](CCC(NCCS(O)(=O)=O)=O)[C@@]1([H])CC[C@@]2([H])[C@]3([H])[C@@H](O)C[C@]4([H])C([2H])([2H])[C@H](O)C([2H])([2H])C[C@]4(C)[C@@]3([H])CC[C@@]21C
分子式 C26H41D4NO6S 分子量 503.7
溶解度 储存条件 -20°C
General tips 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
Shipping Condition 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。

溶解性数据

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1 mg 5 mg 10 mg
1 mM 1.9853 mL 9.9265 mL 19.8531 mL
5 mM 0.3971 mL 1.9853 mL 3.9706 mL
10 mM 0.1985 mL 0.9927 mL 1.9853 mL
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