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Tetramethylpyrazine Sale

(Synonyms: 川芎嗪; Chuanxiongzine; Tetramethylpyrazine) 目录号 : GN10585

An alkaloid with diverse biological activities

Tetramethylpyrazine Chemical Structure

Cas No.:1124-11-4

规格 价格 库存 购买数量
10mM (in 1mL DMSO)
¥385.00
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100mg
¥350.00
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Sample solution is provided at 25 µL, 10mM.

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产品描述

Tetramethylpyrazine (Ligustrazine), an alkylpyrazine isolated from Ligusticum wallichii (Chuan Xiong)[1], is present in french fries, bread, cooked meats, tea, cocoa, coffee, beer, spirits, peanuts, filberts, dairy products and soy products as fragrance and flavouring ingredienexhibits. Tetramethylpyrazine (Ligustrazine) also has potential nootropic and anti-inflammatory activities in rats[2][3].

Tetramethylpyrazine has been extensively used in China for cardiovascular and cerebrovascular diseases for about 40 years. Because of its effectiveness in multisystem, especially in cardiovascular. Tetramethylpyrazine also has been used in various diseases, such as coronary heart disease, diabetes, cancers, and liver injury[1].

References:
[1]. Zhao Y, et al. Mechanisms and Clinical Application of Tetramethylpyrazine (an Interesting Natural Compound Isolated from Ligusticum Wallichii): Current Status and Perspective. Oxid Med Cell Longev. 2016;2016:2124638.
[2]. Wu W, et al. Tetramethylpyrazine protects against scopolamine-induced memory impairments in rats by reversing the cAMP/PKA/CREB pathway. Behav Brain Res. 2013 Sep 15;253:212-6.
[3]. Kao TK, et al. Tetramethylpyrazine reduces cellular inflammatory response following permanent focal cerebral ischemia in rats. Exp Neurol. 2013 Sep;247:188-201.

Chemical Properties

Cas No. 1124-11-4 SDF
别名 川芎嗪; Chuanxiongzine; Tetramethylpyrazine
化学名 2,3,5,6-tetramethylpyrazine
Canonical SMILES CC1=C(N=C(C(=N1)C)C)C
分子式 C8H12N2 分子量 136.2
溶解度 DMF: 5mg/mL,DMSO: 5mg/mL,Ethanol: 25mg/mL,Ethanol:PBS (pH 7.2) (1:5): 0.16mg/mL 储存条件 Stored at RT
General tips 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
Shipping Condition 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。

溶解性数据

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1 mg 5 mg 10 mg
1 mM 7.3421 mL 36.7107 mL 73.4214 mL
5 mM 1.4684 mL 7.3421 mL 14.6843 mL
10 mM 0.7342 mL 3.6711 mL 7.3421 mL
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