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TGFB3 Human, HEK

目录号 : GP20954

Transforming Growth Factor-Beta 3 Human Recombinant, HEK

TGFB3 Human, HEK Chemical Structure

规格 价格 库存 购买数量
1μg
¥840.00
5-10工作日
5μg
¥1,820.00
5-10工作日
100μg
¥21,000.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

产品文档

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产品描述

TGF-b 3 Human Recombinant produced in HEK cells is a non-glycosylated homodimer, having a total molecular weight of 25kDa.The TGF-b 3 is purified by proprietary chromatographic techniques.

Product Data

Purity Greater than 95% as obsereved by SDS-PAGE. Source HEK.
Phycical Appearance Sterile Filtered White lyophilized (freeze-dried) powder. Shipping Condition Shipped at Room temp.
Synonyms Transforming Growth Factor-beta3; TGFB3; ARVD; FLJ16571; TGF-beta3.
Solubility It is recommended to reconstitute the lyophilized TGF-b 3 in sterile 4mM HCl containing 0.1% endotoxin-free recombinant HSA.
Stability Lyophilized TGF-b3 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution TGF-b3 should be stored at 4°C between 2-7 days and for future use below -18°C .For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
Biological Activity The specific activity was determined by the dose-dependent inhibition of IL-4 induced proliferation of mouse HT-2 cells (BALB/c spleen activated by sheep erythrocytes in the presence of IL-2) and is typically 0.1-0.5ng/ml.
Formulation The TGF-b3 was lyophilized from 1mg/ml in 1xPBS.

Introduction

Transforming growth factor betas (TGF Betas) mediate many cell-cell interactions that occur during embryonic development. Three TGF Betas have been identified in mammals. TGF Beta 1, TGF Beta 2 and TGF Beta 3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecule.

Biological Activity

The specific activity was determined by the dose-dependent inhibition of IL-4 induced proliferation of mouse HT-2 cells (BALB/c spleen activated by sheep erythrocytes in the presence of IL-2) and is typically 0.1-0.5ng/ml.

Stability

Lyophilized TGF-b3 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution TGF-b3 should be stored at 4°C between 2-7 days and for future use below -18°C .For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.