Tiger17 (trifluoroacetate salt)
(Synonyms: H-Trp-Cys-Lys-Pro-Lys-Pro-Lys-Pro-Arg-Cys-His-NH2) 目录号 : GC90621一个环状肽。
Sample solution is provided at 25 µL, 10mM.
Quality Control & SDS
- View current batch:
- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Tiger17 is a cyclic peptide and derivative of tigerinin-RC1 and tigerinin-RC2, which are antimicrobial peptides found in crab-eating frog (F. cancrivora) skin secretions.1 It increases the proliferation of HaCaT keratinocytes and human skin fibroblasts when used at concentrations ranging from 5 to 20 µg/ml and increases HaCaT cell migration at 20 µg/ml. Tiger17 increases the recruitment of, and the secretion of TGF-β1 and IL-6 from, RAW 264.7 macrophages. Topical application of tiger17 (20 µg/ml) increases the rate of wound closure and re-epithelialization in a mouse model of full-thickness dermal wounds.
制备储备液 | |||
1 mg | 5 mg | 10 mg | |
1 mM | 0.7264 mL | 3.6319 mL | 7.2637 mL |
5 mM | 0.1453 mL | 0.7264 mL | 1.4527 mL |
10 mM | 0.0726 mL | 0.3632 mL | 0.7264 mL |
第一步:请输入基本实验信息(考虑到实验过程中的损耗,建议多配一只动物的药量) | ||||||||||
给药剂量 | mg/kg | 动物平均体重 | g | 每只动物给药体积 | ul | 动物数量 | 只 | |||
第二步:请输入动物体内配方组成(配方适用于不溶于水的药物;不同批次药物配方比例不同,请联系GLPBIO为您提供正确的澄清溶液配方) | ||||||||||
% DMSO % % Tween 80 % saline | ||||||||||
计算重置 |
计算结果:
工作液浓度: mg/ml;
DMSO母液配制方法: mg 药物溶于 μL DMSO溶液(母液浓度 mg/mL,
体内配方配制方法:取 μL DMSO母液,加入 μL PEG300,混匀澄清后加入μL Tween 80,混匀澄清后加入 μL saline,混匀澄清。
1. 首先保证母液是澄清的;
2.
一定要按照顺序依次将溶剂加入,进行下一步操作之前必须保证上一步操作得到的是澄清的溶液,可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。