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TIMP2 Human, Sf9

目录号 : GP22304

Tissue Inhibitor of Metalloprotease 2 Human Recombinant, Sf9

TIMP2 Human, Sf9 Chemical Structure

规格 价格 库存 购买数量
1μg
¥840.00
5-10工作日
5μg
¥2,030.00
5-10工作日
50μg
¥16,800.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

产品文档

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产品描述

TIMP2 produced in Sf9 Baculovirus cells is a single,glycosylated polypeptide chain containing 200 amino acids (27-220a.a.) andhaving a molecular mass of 22.5kDa.(Molecular size on SDS-PAGE will appear atapproximately 18-28kDa).TIMP2 is expressed with a 6amino acid His tag at C-Terminus and purified by proprietary chromatographictechniques.

Product Data

Purity Greater than 95.0% as determined by SDS-PAGE. Source Sf9,Baculovirus cells.
Phycical Appearance Sterile Filtered clear solution. Shipping Condition Shipped with Ice Packs.
Synonyms TIMPMetallopeptidase Inhibitor 2; Tissue Inhibitor Of Metalloproteinases 2; CSC-21K;Tissue Inhibitor Of Metalloproteinase 2; TIMP-2; DDC8; Metalloproteinaseinhibitor 2.
Amino Acid Sequence CSCSPVHPQQ AFCNADVVIR AKAVSEKEVD SGNDIYGNPI KRIQYEIKQIKMFKGPEKDI EFIYTAPSSA VCGVSLDVGG KKEYLIAGKA EGDGKMHITL CDFIVPWDTL STTQKKSLNHRYQMGCECKI TRCPMIPCYI SSPDECLWMD WVTEKNINGH QAKFFACIKR SDGSCAWYRGAAPPKQEFLD IEDPHHHHHH.
Stability Store at 4°C if entire vial will be used within 2-4weeks.Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrierprotein (0.1% HSA or BSA).
Formulation TIMP2 protein solution (0.25mg/ml) contains PhosphateBuffered Saline (pH 7.4) and 10% glycerol.

Introduction

TIMP2 belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases that take part in degradation of the extracellular matrix. Besides having an inhibitory role against metalloproteinases, the encoded protein has a exclusive part among TIMP family members in its capability to directly suppress the proliferation of endothelial cells. Consequently, the encoded protein is crucial to the conservation of tissue homeostasis by suppressing the production of quiescent tissues as an answer to angiogenic factors, and by inhibiting protease activity in tissues undergoing renovation of the extracellular matrix.

Stability

Store at 4°C if entire vial will be used within 2-4weeks.Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrierprotein (0.1% HSA or BSA).