TNFSF8 Human, Sf9
目录号 : GP20997CD30 Ligand Human Recombinant, Sf9
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greater than 85% as determined by SDS-PAGE. | Source | Sf9,Baculovirus cells. |
| Phycical Appearance | Sterile filtered colorless solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | Tumor Necrosis Factor Superfamily Member 8; TumorNecrosis Factor (Ligand) Superfamily; Member 8; CD153 Antigen; CD30 Ligand; CD30LG;CD30-L; CD30L; Tumor Necrosis Factor (Ligand) Superfamily Member 8; TumorNecrosis Factor Ligand 3A; CD30 Antigen Ligand; TNLG3A; CD153; Tumor necrosisfactor ligand superfamily member 8; TNFSF8; CD30 ligand. | ||
| Amino Acid Sequence | ADPQRTDSIPNSPDNVPLKG GNCSEDLLCI LKRAPFKKSW AYLQVAKHLN KTKLSWNKDG ILHGVRYQDG NLVIQFPGLYFIICQLQFLV QCPNNSVDLK LELLINKHIK KQALVTVCES GMQTKHVYQN LSQFLLDYLQ VNTTISVNVDTFQYIDTSTF PLENVLSIFL YSNSDHHHHHH. | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. | ||
| Formulation | TNFSF8protein solution (0.5mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10%glycerol. | ||
CD30 Ligand (TNFSF8) is a cytokine which is a member of the tumor necrosis factor (TNF) ligand family. The TNFSF8 cytokine is a ligand for TNFRSF8/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The employment of the TNFSF8 cytokine expressed on B cell surface has an inhibitory role in modulating Ig class switch. TNFSF8 enhances cell proliferation of some lymphoma cell lines, while inducing cell death and reducing cell proliferation of other lymphoma cell lines. The pleiotropic biological activities of the TNFSF8 cytokine on different CD30+ lymphoma cell lines has a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.