TRIM21 Human Biotin
目录号 : GP24881Tripartite Motif Containing 21 (RO52) Human Recombinant, Biotinylated
Sample solution is provided at 25 µL, 10mM.
Purity | Greater than 80% as determined by SDS-PAGE. | Source | Sf9 insect cells. |
Phycical Appearance | Sterile Filtered clear solution. | Shipping Condition | Shipped with Ice Packs. |
Synonyms | 52 kDa Ro protein; Sjoegren syndrome type A antigen; SS-A; Ro(SS-A); 52 kDa ribonucleoprotein autoantigen Ro/SS-A; Tripartite motif-containing protein 21; RING finger protein 81; TRIM21; RNF81; RO52; SSA1; SSA; RO-52. | ||
Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.Avoid multiple freeze-thaw cycles. | ||
Formulation | TRIM21 solution is supplied in 20mM HEPES pH-7.6, 0.01mM EDTA and 0.02% SDS. |
TRIM21 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The 52 kDa Ro protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. Ro/SSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Ribonucleoprotein particle is composed of a single polypeptide and one of four small RNA molecules. The RoSSA is present in all mammalian cells studied but has no known function. At least 2 isoforms are present in nucleated and red blood cells, and tissue specific differences in Ro/SSA proteins were identified.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.Avoid multiple freeze-thaw cycles.