Trimesic Acid
(Synonyms: 均苯三甲酸) 目录号 : GC45087
A non-immunoglobin protein scaffold
Cas No.:554-95-0
Sample solution is provided at 25 µL, 10mM.
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Quality Control & SDS
- View current batch:
- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Trimesic acid is a planar benzoic acid that has been used as a non-immunoglobin protein scaffold for studies of protein-protein interactions. It also has various industrial uses in synthesizing adhesive and coating materials, plastics engineering, and as a pharmaceutical intermediate.
| Cas No. | 554-95-0 | SDF | |
| 别名 | 均苯三甲酸 | ||
| Canonical SMILES | O=C(O)C1=CC(C(O)=O)=CC(C(O)=O)=C1 | ||
| 分子式 | C9H6O6 | 分子量 | 210.1 |
| 溶解度 | DMF: 25 mg/ml,DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml,DMSO: 25 mg/ml,Ethanol: 0.2 mg/ml | 储存条件 | Store at -20°C |
| General tips | 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。 为了提高溶解度，请将管子加热至37℃，然后在超声波浴中震荡一段时间。 |
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| Shipping Condition | 评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备RT，或根据请求配备蓝冰。 | ||
| 制备储备液 | |||
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1 mg | 5 mg | 10 mg |
| 1 mM | 4.7596 mL | 23.7982 mL | 47.5964 mL |
| 5 mM | 0.9519 mL | 4.7596 mL | 9.5193 mL |
| 10 mM | 0.476 mL | 2.3798 mL | 4.7596 mL |
| 第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量） | ||||||||||
| 给药剂量 | mg/kg |  |
动物平均体重 | g | |
每只动物给药体积 | ul | |
动物数量 | 只 |
| 第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系GLPBIO为您提供正确的澄清溶液配方） | ||||||||||
| % DMSO % % Tween 80 % saline | ||||||||||
| 计算重置 | ||||||||||
计算结果:
工作液浓度： mg/ml；
DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，
体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL saline，混匀澄清。
1. 首先保证母液是澄清的；
2.
一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。
Carbonyl hypoiodites from pivalic and Trimesic Acid and their silver(I) intermediates
Dalton Trans 2022 Oct 4;51(38):14646-14653.PMID:36093683DOI:10.1039/d2dt01988d.
The first tris(O-I-N) carbonyl hypoiodites have been synthesised based on Trimesic Acid and pyridine or 4-methylpyridine, with their structures definitively confirmed by single crystal X-ray diffraction (SCXRD). The more soluble carbonyl hypoiodites based on pivalic acid have also been studied via NMR, SCXRD, and computational analyses, enabling the study of the direct silver(I) precursor and intermediates of the resulting carbonyl hypoiodites generated using a range of substituted pyridines.
Sodium Chloroacetate Modified Polyethyleneimine/Trimesic Acid Nanofiltration Membrane to Improve Antifouling Performance
Membranes (Basel) 2021 Sep 14;11(9):705.PMID:34564521DOI:10.3390/membranes11090705.
Nanofiltration (NF) is a separation technology with broad application prospects. Membrane fouling is an important bottleneck-restricting technology development. In the past, we prepared a positively charged polyethyleneimine/Trimesic Acid (PEI/TMA) NF membrane with excellent performance. Inevitably, it also faces poor resistance to protein contamination. Improving the antifouling ability of the PEI/TMA membrane can be achieved by considering the hydrophilicity and chargeability of the membrane surface. In this work, sodium chloroacetate (ClCH2COONa) is used as a modifier and is grafted onto the membrane surface. Additionally, 0.5% ClCH2COONa and 10 h modification time are the best conditions. Compared with the original membrane (M0, 17.2 L m-2 h-1), the initial flux of the modified membrane (M0-e, 30 L m-2 h-1) was effectively increased. After filtering the bovine albumin (BSA) solution, the original membrane flux dropped by 47% and the modified membrane dropped by 6.2%. The modification greatly improved the antipollution performance of the PEI/TMA membrane.
Mixing behavior of p-terphenyl-3,5,3',5'-tetracarboxylic acid with Trimesic Acid at the solid-liquid interface
Phys Chem Chem Phys 2021 Nov 24;23(45):25896-25900.PMID:34779445DOI:10.1039/d1cp04770a.
The molecular self-assembly of carboxylic acid molecules on a solid surface plays an important role in understanding the nanoscale-precision construction of functional patterns. In this study, the mixing behavior of p-terphenyl-3,5,3',5'-tetracarboxylic acid (TPTC) and Trimesic Acid (TMA) on a highly oriented pyrolytic graphite surface was studied by scanning tunneling microscopy (STM). The STM images show how the presence of a small percentage of TPTC molecules adsorbed onto TMA molecules can drastically change the on-surface self-assembly behavior of aromatic tetracarboxylic acid by initiating the nucleation and growth of a different polymorph. Molecular mechanics and density functional theory simulations of the adsorption energy and the additional stabilizing energy, induced by hydrogen bonds during assembly formations, provide insights into the relative stability of different assembled structures. Moreover, STM-based "nanoshaving" was conducted to confirm that the template layer underneath the second layer is indeed a random network.
Copper nanoparticles induced, Trimesic Acid grafted cellulose-an effective, non-hazardous processing approach for multifunctional textile with low chemical induction
Cellulose (Lond) 2021;28(18):11609-11624.PMID:34703085DOI:10.1007/s10570-021-04251-5.
Abstract: Cross-linkers have great importance in textile due to the widespread utilization of cellulosic fibers for clothing. Unfortunately, the acute toxicity of formaldehyde-based resins and the poor performance of non-formaldehyde resins still keep the research door open for scientists in this area. Herein, we demonstrated copper nanoparticles induced Trimesic Acid grafted cellulose as a sustainable solution for multifunctional easy-care clothing. Our treated fabric presents crease recovery angle value of 248° comparable to that of most promising citric acid-based cross-linkers at the chemical concentration of Trimesic Acid as low as 2% with a sweeping improvement of around 30% in strength retention, not reported earlier. The relatively low fabric stiffness, without any yellowing, is contributing to the comfort and aesthetic demand while nanoparticles induction promoting utmost antimicrobial need. For the first time, the superiority of the development was validated by interlacing the fabric/finish traits with sustainability building blocks that provide the step forward for rapid industrialization. Furthermore, environmental, health, and safety mapping comparison provides a better understanding of the intensity of hazards that different finishing crosslinkers pose on the environment and public health. With improved performance and superior sustainability, such fabric can act as a preferable alternative to the multifunctional easy-care fabric market. Supplementary information: The online version contains supplementary material available at 10.1007/s10570-021-04251-5.
Quantification of Trimesic Acid in liver, spleen and urine by high-performance liquid chromatography coupled to a photodiode-array detection
J Chromatogr B Analyt Technol Biomed Life Sci 2011 Aug 1;879(23):2311-4.PMID:21727049DOI:10.1016/j.jchromb.2011.06.020.
The quantification of Trimesic Acid, a constitutive organic linker from the biodegradable porous iron(III) trimesate MIL-100(Fe) (MIL stands for Materials from Institut Lavoisier), has been performed in different biological complex media (liver, spleen and urine) using a liquid-liquid extraction procedure. A recovery exceeding 92 wt% was achieved from rat tissues and urine spiked with Trimesic Acid. After extraction, the determination of the Trimesic Acid concentration was realised by using a simple and accurate high-performance liquid chromatography (HPLC) method using photodiode-array detection (PDA) and aminosalicylic acid, as internal standard. Linearity of this method was kept from 0.01 to 100mg of Trimesic Acid per liter of urine and from 0.05 to 5.00 wt% of Trimesic Acid per tissue weight. The limit of detection of the method was 0.01 μg per injection. This method was finally applied to analyze and quantify the amount of Trimesic Acid in rat urine and tissue samples at the different stages of degradation of MIL-100(Fe).