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Tylosin (Tylosin A) Sale

(Synonyms: 泰乐菌素; Tylosin A) 目录号 : GC32084

A macrolide antibiotic

Tylosin (Tylosin A) Chemical Structure

Cas No.:1401-69-0

规格 价格 库存 购买数量
10mM (in 1mL DMSO)
¥491.00
现货
50mg
¥446.00
现货

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Sample solution is provided at 25 µL, 10mM.

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Description

Tylosin is a macrolide antibiotic produced by S. fradiae that has bacteriostatic activity against Gram-positive bacteria.1 It is a mixture of tylosin A, B, C, and D, with tylosin A contributing 80% of its bacteriostatic activity. Tylosin has MIC values of 9.6, 16.4, 0.1, 1, and 0.5 μg/ml for F. necrophorum, A. pyogenes, M. gallisepticum, S. aureus, and S. uberis, respectively.2,3,4 Formulations containing tylosin have been used for the prevention of liver abscesses in cattle.3 Tylosin is an environmental contaminant because it is not fully metabolized by treated livestock and enters the environment through manure-based fertilizers.5

1.Arsic, B., Barber, J., ?iko?, A., et al.16-membered macrolide antibiotics: A review.Int. J. Antimicrob. Agents30238-30280(2017) 2.Bonnier, M., Doré, C., Amédéo, J., et al.In vitro activity of tylosin and tilmicosin against cocci isolated from bovine mastitisRevue Méd. Vét.157(10)486-489(2006) 3.Nagaraja, T.G., and Chengappa, M.M.Liver abscesses in feedlot cattle: A reviewJ. Anim. Sci.76(1)287-298(1998) 4.Jordan, F.T., and Knight, D.The minimum inhibitory concentration of kitasamycin, tylosin and tiamulin for Mycoplasma gallisepticum and their protective effect on infected chicksAvian Pathol.13(2)151-162(1984) 5.Washington, M.T., Moorman, T.B., Soupir, M.L., et al.Monitoring tylosin and sulfamethazine in a tile-drained agricultural watershed using polar organic chemical integrative sampler (POCIS)Sci. Total. Environ.612358-367(2017)

化学性质

Cas No. 1401-69-0 SDF
别名 泰乐菌素; Tylosin A
Canonical SMILES C[C@@H](O[C@@]1([H])O[C@H]([C@H]([C@@H](CC2=O)O)C)[C@H](C[C@H](C(/C=C/C(C)=C/[C@H](CO[C@H](O[C@H](C)[C@@H](O)[C@H]3OC)[C@@H]3OC)[C@@H](CC)O2)=O)C)CC=O)[C@H]([C@@H]([C@H]1O)N(C)C)O[C@@](O[C@@H](C)[C@@H]4O)([H])C[C@]4(O)C
分子式 C46H77NO17 分子量 916.1
溶解度 DMSO : ≥ 100 mg/mL (109.16 mM);Water : < 0.1 mg/mL (insoluble) 储存条件 Store at -20°C
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储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
Shipping Condition 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。

溶解性数据

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1 mg 5 mg 10 mg
1 mM 1.0916 mL 5.4579 mL 10.9158 mL
5 mM 0.2183 mL 1.0916 mL 2.1832 mL
10 mM 0.1092 mL 0.5458 mL 1.0916 mL
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