UGT1A1 Human
目录号 : GP22376UDP Glucuronosyltransferase 1 Family Polypeptide A1 Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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UGT1A1 Human Recombinant produced in E.Coli is a single,non-glycosylated polypeptide chain containing 488 amino acids (26-490 a.a) andhaving a molecular mass of 54.7kDa.UGT1A1 is fused to a 23 amino acid His-tag at N-terminus& purified by proprietary chromatographic techniques.
| Purity | Greater than 90.0% as determined by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered clear solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | UDP Glucuronosyltransferase 1 Family; Polypeptide A1; UGT1;GNT1; UDP Glycosyltransferase 1 Family; Polypeptide A1; Bilirubin-SpecificUDPGT Isozyme 1; UDP-Glucuronosyltransferase 1-A; UDP-Glucuronosyltransferase1A1; EC 2.4.1.17; UDPGT 1-1; BILIQTL1; HUG-BR1; UGT1-01; UGT-1A; UGT1*1; UGT1.1;UGT1A; Bilirubin UDP-Glucuronosyltransferase Isozyme 1; BilirubinUDP-Glucuronosyltransferase 1-1; UDP-Glucuronosyltransferase 1-1; UDPGT; UDP-glucuronosyltransferase1-1. | ||
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSHAGKILL IPVDGSHWLS MLGAIQQLQQ RGHEIVVLAP DASLYIRDGA FYTLKTYPVPFQREDVKESF VSLGHNVFEN DSFLQRVIKT YKKIKKDSAM LLSGCSHLLH NKELMASLAE SSFDVMLTDPFLPCSPIVAQ YLSLPTVFFL HALPCSLEFE ATQCPNPFSY VPRPLSSHSD HMTFLQRVKN MLIAFSQNFLCDVVYSPYAT LASEFLQREV TVQDLLSSAS VWLFRSDFVK DYPRPIMPNM VFVGGINCLH QNPLSQEFEAYINASGEHGI VVFSLGSMVS EIPEKKAMAI ADALGKIPQT VLWRYTGTRP SNLANNTILV KWLPQNDLLGHPMTRAFITH AGSHGVYESI CNGVPMVMMP LFGDQMDNAK RMETKGAGVT LNVLEMTSED LENALKAVINDKSYKENIMR LSSLHKDRPV EPLDLAVFWV EFVMRHKGAP HLRPAAHDLT WYQYHSLD. | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. | ||
| Formulation | UGT1A1 protein solution (1mg/ml) containing 20mM Tris-HCl(pH8.0) and 10% glycerol. | ||
UDP Glucuronosyltransferase 1 Family Polypeptide A1, also known as UGT1A1 has a main importance in the conjugation as well as subsequent elimination of potentially toxic xenobiotics and endogenous compounds. UGT1A1 is also capable of catalyzing glucuronidation of 17beta, 17alpha, 1-hydroxypyrene, 4-methylumbelliferone, 1-naphthol, paranitrophenol, scopoletin, and umbelliferone.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.