USP15 Human
目录号 : GP24965Ubiquitin Specific Peptidase 15 Human Recombinant
Sample solution is provided at 25 µL, 10mM.
Purity | Greater than 90% as determined by SDS-PAGE. | Source | Escherichia Coli. |
Phycical Appearance | Sterile filtered colorless solution. | Shipping Condition | Shipped with Ice Packs. |
Synonyms | Ubiquitin Specific Peptidase 15; Ubiquitin Carboxyl-Terminal Hydrolase 15; Deubiquitinating Enzyme 15; Ubiquitin-Specific-Processing Protease 15; Ubiquitin Specific Protease 15; Ubiquitin Thiolesterase 15; KIAA0529; UNPH4; UNPH-2; EC 3.4.19.12; EC 3.1.2.15. | ||
Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSMAEGGAA DLDTQRSDIA TLLKTSLRKG DTWYLVDSRW FKQWKKYVGF DSWDKYQMGD QNVYPGPIDN SGLLKDGDAQ SLKEHLIDEL DYILLPTEGW NKLVSWYTLM EGQEPIARKV VEQGMFVKHC KVEVYLTELK LCENGNMNNV VTRRFSKADT IDTIEKEIRK IFSIPDEKET RLWNKYMSNT FEPLNKPDST IQDAGLYQGQ VLVIEQKNED GTWPRGPSTP KKPLEQSC | ||
Stability | Store at 4°C if entire vial will be used within 2-4 weeks. | ||
Formulation | The USP15 solution contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 1mM DTT and 10% glycerol. |
USP15 belongs to the ubiquitin specific protease (USP) family of deubiquitinating enzymes which has a vital role in ubiquitin-dependent processes through polyubiquitin chain disassembly and hydrolysis of ubiquitin-substrate bonds. USP15 connects with the COP9 signalosome, and takes part in transforming growth factor beta signalling through deubiquitination of receptor-activated SMAD transcription factors. Alternatively spliced transcript variants encoding multiple isoforms of this gene are known, and a pseudo gene of USP15 is sited on the long arm of chromosome 2.
Store at 4°C if entire vial will be used within 2-4 weeks.