VEGF165, Human(HEK 293-expressed)

Vascular Endothelial Growth Factor (VEGF) is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, Vascular Endothelial Growth Factor (VEGF) plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates Vascular Endothelial Growth Factor (VEGF) in the induction of tumor metastasis and intra-ocular neovascular syndromes. Vascular Endothelial Growth Factor (VEGF) signals through the three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product.

VEGF-165; Vascular Endothelial Growth Factor 165; VPF; Folliculostellate cell-derived growth factor; Glioma-derived endothelial cell mitogen; Vascular Permeability Factor

1.Antonin Sedlar, et al.Growth FactorsVEGF-A and FGF-2 as Multifunctional Biomolecules Governing Cell Adhesion and Proliferation.IntJ Mol Sci.(2021-02)

Vascular Endothelial Growth Factor（VEGF）是一种强效的生长和血管生成细胞因子。