Home>>Peptides>>WaTx (36-68) (scorpion) (trifluoroacetate salt)

WaTx (36-68) (scorpion) (trifluoroacetate salt)

(Synonyms: Wasabi Receptor Toxin (36-68)) 目录号 : GC91865

Wasabi receptor toxin (WaTx) (36-68) is a cell-penetrating peptide that corresponds to the mature toxin sequence and is an activator of transient receptor potential ankyrin 1 (TRPA1).

WaTx (36-68) (scorpion) (trifluoroacetate salt) Chemical Structure

规格 价格 库存 购买数量
1 mg
¥966.00
现货
5 mg
¥4,354.00
现货
10 mg
¥8,218.00
现货

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Sample solution is provided at 25 µL, 10mM.

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Wasabi receptor toxin (WaTx) (36-68) is a cell-penetrating peptide that corresponds to the mature toxin sequence and is an activator of transient receptor potential ankyrin 1 (TRPA1).[1] It selectively induces currents in HEK293T cells expressing human TRPA1 (EC50 = 15 nM) over cells expressing human TRP melastatin 8 (TRPM8) or human TRP vanilloid 1 (TRPV1) at 100 nM or rat voltage-gated potassium channel 1.2 (Kv1.2), rat Kv2.1, rat Kv3.1, or rat Kv4.3 at 1,000 nM. WaTx induces nocifensive behavior in wild-type but not Trpa1-/- mice.

References:
[1].King, J.V.L., Emrick, J.J., Kelly, M.J.S., et al.A cell-penetrating scorpion toxin enables mode-specific modulation of TRPA1 and painCell178(6)1362-1374(2019).

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1 mg 5 mg 10 mg
1 mM 0.2594 mL 1.2969 mL 2.5938 mL
5 mM 0.0519 mL 0.2594 mL 0.5188 mL
10 mM 0.0259 mL 0.1297 mL 0.2594 mL
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