ZFAND5 Human
目录号 : GP25043Zinc Finger, AN1-Type Domain 5 Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greater than 85.0% as determined by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered colorless solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | Zinc Finger; AN1-Type Domain 5; Zinc Finger Protein 216; ZNF216;Zinc Finger A20 Domain-Containing Protein 2; Zinc Finger; A20 Domain Containing2; ZA20D2; AN1-Type Zinc Finger Protein 5; ZFAND5A; AN1-type zinc fingerprotein 5; Zinc finger A20 domain-containing protein 2; Zinc finger protein 216. | ||
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSMAQETNQ TPGPMLCSTG CGFYGNPRTN GMCSVCYKEH LQRQQNSGRMSPMGTASGSN SPTSDSASVQ RADTSLNNCE GAAGSTSEKS RNVPVAALPV TQQMTEMSIS REDKITTPKTEVSEPVVTQP SPSVSQPSTS QSEEKAPELP KPKKNRCFMC RKKVGLTGFD CRCGNLFCGL HRYSDKHNCPYDYKAEAAAK IRKENPVVVA EKIQRI. | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. | ||
| Formulation | ZFAND5 protein solution (0.5mg/ml) containing 20mM Phosphatebuffer saline (pH 8.0), 30% glycerol and 1mM DTT. | ||
Zinc Finger, AN1-Type Domain 5, also known as ZFAND5 is implicated inprotein degradation through the ubiquitin-proteasome system. ZFAND5 performs byanchoring ubiquitinated proteins to the proteasome and takes part inubiquitin-mediated protein degradation during muscle atrophy. Furthemore,ZFAND5 plays a role in the regulation of NF-kappa-B activation as well asapoptosis. ZFAND5 inhibits NF-kappa-B activation as well as tumor necrosisfactor (TNF), IL-1 and TLR4-induced NF-kappa-B activation.
Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.