Zilpaterol (hydrochloride)
(Synonyms: 盐酸齐帕特罗) 目录号 : GC48268
A β-adrenergic agonist
Cas No.:119520-06-8
Sample solution is provided at 25 µL, 10mM.
;)
,-1-7$$$37316672.jpg');)
;)
;)
$$$36806353.jpg');)
;33(7)%EF%BC%9A546-561$$$37156877.jpg');)
;)
;)
;)
%201124-1138.$$$35908550.jpg');)
%20766-780.$$$37100057.jpg');)
%20418-432.$$$36893736.jpg');)
%EF%BC%9A-240-255.$$$35108512.jpg');)
533-545$$$36543525.jpg');)
%201-13.$$$36600053.jpg');)
;)
Zilpaterol is a β-adrenergic receptor agonist that putatively through activation of protein kinase A increases protein synthesis in skeletal muscle fibers, as well as reduces lipogenesis and increases lipolysis in adipose tissues.1,2 It was approved by the FDA in 2006 as a veterinary food additive for the purpose of increasing lean body weight and improving feed efficiency in commercial beef cattle.3
1.AvendaÑo-Reyes, L., Torres-RodrÍguez, V., Meraz-Murullo, F.J., et al.Effects of two β-adrenergic agonists on finishing performance, carcass characteristics, and meat quality of feedlot steersJ. Anim. Sci.84(12)3259-3265(2006) 2.Miller, E.K., Chung, K.Y., Hutcheson, J.P., et al.Zilpaterol hydrochloride alters abundance of β-adrenergic receptors in bovine muscle cells but has little effect on de novo fatty acid biosynthesis in bovine subcutaneous adipose tissue explantsJ. Anim. Sci.90(4)1317-1327(2012) 3.Delmore, R.J., Hodgen, J.M., and Johnson, B.J.Perspectives on the application of zilpaterol hydrochloride in the United States beef industryJ. Anim. Sci.88(8)2825-2828(2010)
| Cas No. | 119520-06-8 | SDF | |
| 别名 | 盐酸齐帕特罗 | ||
| Canonical SMILES | O=C1NC2=CC=CC3=C2N1CC[C@H](NC(C)C)[C@H]3O.Cl | ||
| 分子式 | C14H19N3O2.HCl | 分子量 | 297.8 |
| 溶解度 | DMF: 0.1 mg/ml,DMSO: 1 mg/ml,PBS (pH 7.2): 10 mg/ml | 储存条件 | Store at -20°C |
| General tips | 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。 为了提高溶解度，请将管子加热至37℃，然后在超声波浴中震荡一段时间。 |
||
| Shipping Condition | 评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备RT，或根据请求配备蓝冰。 | ||
| 制备储备液 | |||
 |
1 mg | 5 mg | 10 mg |
| 1 mM | 3.358 mL | 16.7898 mL | 33.5796 mL |
| 5 mM | 0.6716 mL | 3.358 mL | 6.7159 mL |
| 10 mM | 0.3358 mL | 1.679 mL | 3.358 mL |
| 第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量） | ||||||||||
| 给药剂量 | mg/kg |  |
动物平均体重 | g | |
每只动物给药体积 | ul | |
动物数量 | 只 |
| 第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系GLPBIO为您提供正确的澄清溶液配方） | ||||||||||
| % DMSO % % Tween 80 % saline | ||||||||||
| 计算重置 | ||||||||||
计算结果:
工作液浓度： mg/ml；
DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，
体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL saline，混匀澄清。
1. 首先保证母液是澄清的；
2.
一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。
Quality Control & SDS
- View current batch:
- Purity: >95.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet